Description
AMG-1 is a potent inhibitor of human c-Met and RON with IC50 of 4 and 9 nmol/L respectively.
Alias
AUTS9, HGFR, RCCP2, c-Met
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Synonyms
AUTS9, HGFR, RCCP2, c-Met
Molecular Formula
C31H29FN4O5
Chemical Name
N-(3-fluoro-4-(7-methoxyquinolin-4-yloxy)phenyl)-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL