Description
Alvocidib is a broad-spectrum inhibitor of CDKs and targets their ATP binding sites. It promotes cell cycle arrest and apoptosis, induces differentiation, blocks transcription elongation, and inhibits angiogenesis.
Appearance
Light yellow solid
Molecular Weight
401.8 Da
Stability
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Synonyms
CPB, Flavopiridol, HL-275, HMR-1275
Molecular Formula
C21H20ClNO5
Solubility
Soluble in DMSO