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Alsterpaullone
Cat No.
CEI-0957
Description
A potent and selective inhibitor of GSK-3beta and CDK5/p25. Potent inhibitor of CDK1/Cyclin B (IC50=35 nM). Induces apoptosis. Inhibits angiogenesis.
Abbr
Alsterpaullone(GSK3B, CDK5, CDK5R1)
Alias
9-Nitro-7, 12-dihydroindolo-[3, 2-d][1] benzazepin-6(5)-one
Appearance
Brown crystalline powder
Product Overview
GSK-3beta and CDK5/p25 inhibitor.
CAS No.
237430-03-4
Molecular Weight
293.3
Purity
>96% (TLC); NMR (Conforms)
Synonyms
9-Nitro-7,12-dihydroindolo-[3,2-d][1] benzazepin-6(5)-one
Targets
GSK-3beta, CDK5/p25
Molecular Formula
C16H11N3O3
Solubility
May be dissolved in DMSO (10 mg/ml)
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