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AG-1296
Cat No.
CEI-0954
Description
A potent inhibitor of PDGF receptor tyrosine kinase (PDGFRalpha and beta), IC50=1 µM. Also inhibits FGF receptor tyrosine kinase, c-kit and FLT3 and reverses transformation induced by activated FLT3. Induces apoptosis in a small-cell lung cancer cell line (H526). Cell permeable.
Abbr
AG-1296(PDGFRB)
Alias
6, 7-Dimethoxy-3-phenylquinoxaline
Product Overview
PDGFR Inhibitor
CAS No.
146535-11-7
Molecular Weight
266.3
Purity
>98% (TLC); NMR (Conforms)
Synonyms
6,7-Dimethoxy-3-phenylquinoxaline
Targets
PDGFR
Molecular Formula
C16H14N2O2
Solubility
May be dissolved in DMSO
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