Products
Online Inquiry
Our Products Cannot Be Used As Medicines Directly For Personal Use.
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
Cat No.
EXWM-3988
Description
This multiunctional enzyme catalyses both the synthesis and hydrolysis of cyclic ADP-ribose, a calcium messenger that can mobilize intracellular Ca2+ stores and activate Ca2+ influx to regulate a wide range of physiological processes. In addition, the enzyme also catalyses EC 2.4.99.20, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase. cf. EC 3.2.2.5, NAD+ glycohydrolase.
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
9032-65-9
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
NAD+ nucleosidase; NADase (ambiguous); DPNase (ambiguous); DPN hydrolase (ambiguous); NAD hydrolase (ambiguous); nicotinamide adenine dinucleotide nucleosidase (ambiguous); NAD glycohydrolase (misleading); NAD nucleosidase (ambiguous); nicotinamide adenine dinucleotide glycohydrolase (misleading); CD38 (gene name); BST1 (gene name)
Reaction
NAD+ + H2O = ADP-D-ribose + nicotinamide (overall reaction); (1a) NAD+ = cyclic ADP-ribose + nicotinamide; (1b) cyclic ADP-ribose + H2O = ADP-D-ribose
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Download
Download Datasheet