Adenosine 5'-diphosphoribose sodium salt (ADP-Ribose) is used as the basic building block used as a substrate in the formation of poly(ADP-ribose) by members of the poly(ADP-ribose) polymerase (PARP) family. Poly(ADP-ribose) formation and degradation are an important components of DNA repair and apoptosis signaling.
Applications
A substrate used in the formation of poly(ADP-ribose) by members of the poly(ADP-ribose) polymerase (PARP) family