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Ac-IETD-AFC

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Cat No.

CSUB-0742

Description

Ac-IETD-AFC is a fluorogenic substrate for caspase-8/caspase-3 processing enzyme and granzyme B. It is also a substrate for caspase-10. The IETD sequence is based on caspase-3 proenzyme cleavage site.

Applications

A substrate for caspase-8/caspase-3 processing enzyme and granzyme B

Form

Solid

CAS No.

211990-57-7

Molecular Weight

729.65

Storage

Store at -20° C

Synonyms

Caspase-8 Substrate IETD-AFC; N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-(trifluoromethyl)coumarin

Molecular Formula

C31H38F3N5O12

MDL Number

MFCD02094703

Solubility

Soluble in DMSO.

Substrates

Chymotrypsin