Products
Online Inquiry
Our Products Cannot Be Used As Medicines Directly For Personal Use.
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
ABT-888
Cat No.
CEI-0636
Description
Potent inhibitor of PARP-1 and PARP-2 (potency ≤5 nM in vitro). Does not inhibit other NAD-binding enzymes. Has minimal CYP450 inhibition and induction. Shows broad spectrum of chemo- and radio-potentiation. Does not show inherent cytotoxicity and shows no single agent activity in tumor models.
Appearance
Orange solid
Product Overview
A PRP-1 and PARP-2 inhibitor
CAS No.
912445-05-7
Molecular Weight
242.27
Purity
>98% by TLC
Storage
-20 centigrade
Targets
Protein Synthesis
Molecular Formula
C₁₃H₁₆N₄O.2HCl
Chemical Name
2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide . dihydrochloride
Solubility
DMSO (100 mM) or EtOH (50 mM)
Shipping Conditions
Gel pack
Download
Download Datasheet