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A-674563

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Cat No.

CEI-0105

Description

A-674563

CAS No.

552325-73-2

Molecular Weight

358.44

Purity

>99%

Storage

2 years at -20 centigrade

Targets

Akt1

Molecular Formula

C22H22N4O

Solubility

In vitro

A-674563 can blcok the tumor cell proliferation with EC50 of 0.4 uM. A-674563 inhibit the phosphorylation of Akt downstream targets in a dose-dependent manner. In STS cells, A-674563 inhibit Akt and induce G2 cell cycle arrest and apoptosis.