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spore photoproduct lyase
Cat No.
EXWM-4929
Description
This enzyme is a member of the 'AdoMet radical' (radical SAM) family. The enzyme binds a [4Fe-4S] cluster. The cluster is coordinated by 3 cysteines and an exchangeable SAM molecule. The 5'-deoxy-adenosine radical formed after electron transfer from the [4Fe-4S] cluster to the S-adenosyl-L-methionine, initiates the repair by abstracting the C-6 hydrogen of the spore photoproduct lesion. During the second part of the repair process the SAM molecule is regenerated.
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
37290-70-3
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
SAM; SP lyase; SPL; SplB; SplG
Reaction
(5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine (in double-helical DNA) = thymidylyl-(3'→5')-thymidylate (in double-helical DNA)
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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