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renalase
Cat No.
EXWM-1587
Description
Requires FAD. Renalase, previously thought to be a hormone, is a flavoprotein secreted into the blood by the kidney that oxidizes the 1,2-dihydro- and 1,6-dihydro- isomeric forms of β-NAD(P)H back to β-NAD(P)+. These isomeric forms, generated by nonspecific reduction of β-NAD(P)+ or by tautomerization of β-NAD(P)H, are potent inhibitors of primary metabolism dehydrogenases and pose a threat to normal respiration.
Form
Liquid or lyophilized powder
Enzyme Commission Number
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
αNAD(P)H oxidase/anomerase (incorrect); NAD(P)H:oxygen oxidoreductase (H2O2-forming, epimerising) (incorrect)
Reaction
(1) 1,2-dihydro-β-NAD(P) + H+ + O2 = β-NAD(P)+ + H2O2; (2) 1,6-dihydro-β-NAD(P) + H+ + O2 = β-NAD(P)+ + H2O2
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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