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premnaspirodiene oxygenase
Cat No.
EXWM-0722
Description
A heme-thiolate protein (P-450). The enzyme from the plant Hyoscymus muticus also hydroxylates valencene at C-2 to give the α-hydroxy compound, nootkatol, and this is converted into nootkatone. 5-Epiaristolochene and epieremophilene are hydroxylated at C-2 to give a 2β-hydroxy derivative which is not further oxidized.
Form
Liquid or lyophilized powder
Enzyme Commission Number
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
HPO; Hyoscymus muticus premnaspirodiene oxygenase
Reaction
(-)-vetispiradiene + 2 NADPH + 2 H+ + 2 O2 = solavetivone + 2 NADP+ + 3 H2O (overall reaction); (1a) (-)-vetispiradiene + NADPH + H+ + O2 = solavetivol + NADP+ + H2O; (1b) solavetivol + NADPH + H+ + O2 = solavetivone + NADP+ + 2 H2O
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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