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Native Streptolysin O from Escherichia coli
Cat No.
NATE-1161
Description
Streptolysin O possesses a single polypeptide chain with a molecular weight of f62 kDa. Streptolysin O binds to membrane cholesterol and oligomerizes to create a ring structure that consists of 45 to 50 units. The ring structure inserts into the membrane to make a large pore (25 to 30 nm), which DNA, RNA, peptides and proteins may pass. It is thiol-activated. It is inhibited by allicin, an active component of garlic.
Abbr
SLO, Native (E. coli)
Alias
SLO
Source
Escherichia coli
Applications
Used in the formulation of anti-streptolysin O (ASO) assays which are used in the diagnosis of group A Streptococcal based illnesses.
Appearance
Clear to slightly cloudy solution.
Product Overview
Streptolysin-O is one of several toxic immunogenic exoenzymes produced by most strains of group A and many strains of groups C and G, β-hemolytic streptococci. The O in the name stands for oxygenlabile; the other related toxin being oxygen-stable streptolysin-S. The main function of streptolysin O is to cause hemolysis (the breaking open of red blood cells) in particular, beta-hemolysis.
Enzyme Commission Number
EC.3.2.2.5
CAS No.
9032-65-9
Purity
> 90%
Concentration
> 0.8 mg/mL (Biorad method); > 0.68 mg/mL (A280 method)
Synonyms
Streptolysin O; 98072-47-0; SLO
Download
Download Datasheet| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-0671 | Native Streptococcus pyogenes Streptolysin O | 98072-47-0 | Streptococcus pyogenes | Inquiry |