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Native Flavobacterium heparinum Heparinase I and III Blend
Cat No.
NATE-0337
Description
Heparin-degrading lyase that recognizes heparin sulfate proteoglycan as its primary substrate. Heparinase I and III plays vital role in various biological processes: modulate cell-growth factor interactions, cell-lipoprotein interactions, neovascularization. It cleaves highly sulphated polysaccharide chains in presence of 2-O-sulfated α-L-idopyranosyluronic acid and β-D-glucopyranosyluronic acid residues of polysaccharides.
Abbr
Heparinase I and III, Native (Flavobacterium heparinum)
Alias
Heparinase
Source
Flavobacterium heparinum
Applications
Heparinase I and III may be used for the study of heparin production during fermentation and specific activity of heparinise.
Product Overview
Heparinase is an inducible, non-extracellular heparin-degrading enzyme. Three types of heparinises are produced by Flavobacterium heparinum and contains specific sequences of heparin.
Unit Definition
One unit will form 0.1 micromole of unsaturated uronic acid per hour at 7.5 at 25 degrees C using Heparin, Sodium as substrate for heparinase I. One unit will form 0.1 micromole of unsaturated uronic acid per hour at 7.5 at 25 degrees C using bovine kidney Heparan, Sulfate as substrate for heparinase III.
Storage
−20°C
Warnings
Enzyme Commission Numbers: 4.2.2.7 Hep I and 4.2.2.8 Hep III
Synonyms
Heparinase; Heparin lyase; Heparin eliminase; Heparin-sulfate lyase; Heparin-sulfate eliminase; Heparitin-sulfate lyase; Heparinase I; Heparinase III
Download
Download Datasheet"Heparinase" Total Products Page
| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-1948 | Heparinase III from Flavobacterium heparinum, Recombinant | EC 4.2.2.8 | 37290-86-1 | E.coli | Inquiry |
| NATE-1946 | Heparinase I from Flavobacterium heparinum, Recombinant | EC 4.2.2.7 | 9025-39-2 | E.coli | Inquiry |
| NATE-1947 | Heparinase II from Flavobacterium heparinum, Recombinant | 149371-12-0 | E.coli | Inquiry | |
| NATE-1550 | Heparin-sulfate lyase from Bacteroides thetaiotaomicron, Recombinant | EC 4.2.2.8 | 37290-86-1 | E. coli | Inquiry |