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Native Bovine L-Glutamic Dehydrogenase

Cat No.
NATE-0392
Description
L-glutamic dehydrogenase catalyzes the conversion of glutamate to α-ketoglutarate. Mammalian forms of this enzyme, including this bovine form, can use either NADP (H) or NAD (H) as coenzymes. L-glutamic dehydrogenase plays a unique role in mammalian metabolism. The reverse reaction catalyzed by this enzyme is the only pathway by which ammonia can become bound to the α-carbon atom of an α-carboxylic acid and thus, is the only source of de novo amino acid synthesis in mammalian species.
Abbr
L-GLDH, Native (Bovine)
Alias
L-GLDH
Source
Bovine liver
Species
Bovine
Form
Type I, ammonium sulfate suspension, Suspension in 2.0 M (NH4)2SO4 solution; Type II, lyophilized powder, Contains primarily Citrate buffer salt; Type III, aqueous glycerol solution, Solution in 50% glycerol, pH 7.3.
Enzyme Commission Number
EC 1.4.1.3
Activity
Type I, > 40 units/mg protein; Type II, > 20 units/mg protein; Type III, > 35 units/mg protein.
CAS No.
9029-12-3
Unit Definition
One unit will reduce 1.0 μmole of α-ketoglutarate to L-glutamate per min at pH 7.3 at 25°C, in the presence of ammonium ions.
Storage
2-8°C
Warnings
Protein determined by biuret
Pathway
Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; D-Glutamine and D-glutamate metabolism, organism-specific biosystem
Function
ATP binding; GTP binding; glutamate dehydrogenase (NAD+) activity
Synonyms
glutamic dehydrogenase; glutamate dehydrogenase [NAD (P)]; 9029-12-3; glutamate dehydrogenase [NAD (P)+]; EC 1.4.1.3; L-GLDH; L-Glutamate:NAD[P]+ Oxidoreductase (deaminating)

"GLDH" Total Products Page

Catalog Product Name EC No. CAS No. Source Price
NATE-1802 L-Glutamate Dehydrogenase (Crude Enzyme) EC 1.4.1.2 9001-46-1 E. coli Inquiry
NATE-1701 Glutamate Dehydrogenase from Thermophilic Bacterium, recombinant EC 1.4.1.2 9001-46-1 E. coli Inquiry
NATE-1037 Native Glutamate dehydrogenase (NADP+) from Yeast EC 1.4.1.4 2604121 Yeast Inquiry
NATE-1145 Glutamate dehydrogenase, Recombinant EC 1.4.1.2 9001-46-1 Inquiry

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