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infectious pancreatic necrosis birnavirus Vp4 peptidase
Cat No.
EXWM-4110
Description
Infectious pancreatic necrosis virus (IPNV) is a birnavirus that causes an acute, contagious disease in young salmonid fish. As with most viruses that infect eukaryotic cells, the proteolytic processing of viral precursor proteins is a crucial step in the life cycle of this virus. pVP2 is converted into VP2 by cleavage near the carboxy end of pVP2. This cleavage is most likely due to host-cell proteases rather than VP4. Differs from most serine peptidases in not having the catalytic triad Ser-His-Asp. Belongs in peptidase family S50.
Form
Liquid or lyophilized powder
Enzyme Commission Number
EC 3.4.21.115
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
infectious pancreatic necrosis virus protease; IPNV Vp4 protease; IPNV Vp4 peptidase; NS protease; NS-associated protease; Vp4 protease
Reaction
Cleaves the (Ser/Thr)-Xaa-Ala┼(Ser/Ala)-Gly motif in the polyprotein NH2-pVP2-VP4-VP3-COOH of infectious pancreatic necrosis virus at the pVP2-VP4 and VP4-VP3 junctions
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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