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Fructose 1,6-bisphosphatase from Human, Recombinant
Cat No.
NATE-1576
Description
Fructose 1,6-bisphosphatase (FBPase; EC 3.1.3.11) is an enzyme in the liver that converts fructose-1,6-bisphosphate to fructose 6-phosphate in gluconeogenesis. Fructose bisphosphatase catalyses the reverse of the reaction which is catalysed by phosphofructokinase, which is involved in the process of glycolysis. These enzymes only catalyse the reaction in one direction each, and are regulated by metabolites such as fructose 2,6-bisphosphate so that high activity of one of the two enzymes is accompanied by low activity of the other. It is involved in many different metabolic pathways and found in most organisms. FBPase requires metal ions for catalysis (Mg2+ and Mn2+ being preferred) and the enzyme is potently inhibited by Li+.
Abbr
FBPase, Recombinant (Human)
Alias
FBPase
Source
E. coli
Species
Human
Form
Liquid. Storage Buffer: 50 mM potassium phosphate pH-7.4, 50 mM sodium chloride, 0.5 mM ethylenediaminetetraaceticacid, and 2.5% glycerol.
Enzyme Commission Number
EC 3.1.3.11
Activity
1525 pmol/min/ug
Molecular Weight
36.8 kDa
Purity
> 90% (densitometry)
Unit Definition
One unit is defined as the amount of enzyme that will convert 1 nmol of NADP to NADPH at 30 °C.
Storage
Stable for > 6 months at -80°C
Synonyms
Fructose-bisphosphatase; EC 3.1.3.11; FBPase; Hexose diphosphatase
Download
Download Datasheet| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| EXWM-3614 | fructose-bisphosphatase | EC 3.1.3.11 | 9001-52-9 | Inquiry |