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chloramphenicol O-acetyltransferase
Cat No.
EXWM-2205
Description
Chloramphenicol acetyltransferase (or CAT) is a bacterial enzyme (EC 2.3.1.28) that detoxifies the antibiotic chloramphenicol and is responsible for chloramphenicol resistance in bacteria. This enzyme covalently attaches an acetyl group from acetyl-CoA to chloramphenicol, which prevents chloramphenicol from binding to ribosomes. A histidine residue, located in the C-terminal section of the enzyme, plays a central role in its catalytic mechanism.
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
9040-07-7
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
chloramphenicol acetyltransferase; chloramphenicol acetylase; chloramphenicol transacetylase; CAT I; CAT II; CAT III
Reaction
acetyl-CoA + chloramphenicol = CoA + chloramphenicol 3-acetate
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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