A non-selective, reversible and competitive inhibitor of NOS isoforms in vitro. The IC50 values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.71, 0.78, and 5.8 µM, respectively. However, it shows good anti-nociceptive effects in vivo without affecting blood pressure via inhibition of eNOS.
Alias
7-NI
Appearance
White solid
Product Overview
A non-selective, reversible and competitive inhibitor of NOS isoforms in vitro.
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