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17-DMAG hydrochloride

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Cat No.

CEI-0535

Description

A water-soluble analog of 17-AAG that displays better stability and low in vivo toxicity similar to 17-AAG, but undergoes limited metabolism compared to 17-AAG. Binds specifically to heat shock protein90 (Hsp90) in a manner similar to geldanamycin.

Alias

Alvespimycin

Appearance

White to off-white solid

Product Overview

A Hsp90 inhibitor

CAS No.

467214-21-7

Molecular Weight

386.42

Purity

>95% by HPLC

Storage

-20 centigrade

Synonyms

Alvespimycin

Targets

HSP90

Molecular Formula

C₃₂H₄₈N₄O₈•HCl

Chemical Name

17-(Dimethylaminoethylamino)-17-demethoxygeldanamycin Hydrochloride

Solubility

DMSO (20 mM)

Shipping Conditions

Gel pack