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1400W dihydrochloride
Cat No.
CEI-0541
Description
Cell-permeable. A slow, tight binding and highly selective inhibitor of iNOS (inducible nitric oxide synthase/NOS II) (Kd >97 nM). In contrast, inhibition of nNOS and eNOS is weaker and rapidly reversible with Kᵢ values of 2 and 50 µM respectively. Inhibits tumor growth in vivo. Prevents circulatory failure but not organ injury induced by endotoxin. Displays protective effects in oxygen-deprived brain slices.
Alias
N-(3-(Aminomethyl)benzyl)acetamidine . 2HCl
Appearance
White solid
Product Overview
A highly selective iNOS inhibitor
CAS No.
214358-33-5
Molecular Weight
523.88
Purity
>95%
Storage
-20 centigrade
Synonyms
N-(3-(Aminomethyl)benzyl)acetamidine . 2HCl
Targets
NOS2
Molecular Formula
C 10 H 15 N 3 . 2HCl
Solubility
Acetic Acid (5%) or 10 mM HCl
Shipping Conditions
Gel pack
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