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(S)-HDAC-42
Cat No.
CEI-0998
Description
S)-HDAC-42 is a strong inhibitor of HDACs. It decreases the viability of prostate cancer cell lines by increasingthe expression of p21 and the acetylation of histone H3 while decreasing Akt phosphorylation and Bcl-XL expression. The inhibitor suppresses the growth of PC-3 tumor xenografts, reducing levels of phospho-Akt and Bcl-XL protein in tumors.
Abbr
(S)-HDAC-42(HDACs)
Appearance
A crystalline solid.
CAS No.
935881-37-1
Molecular Weight
312.4
Purity
>95%
Storage
Store at or below -20 centigrade for up to two years.
Targets
HDACs
IC50
16 nM
Molecular Formula
C8H20N2O3
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