Description
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation.
Purity
Determined by decrease in absorbance at 340 nm on enzymatic reduction with GR*at pH 10.0 (> 95%) *GR = Glutathion reductase (yeast) (EC 1.6.4.2.)
Structure
C21H26N7O17P3Na4
Specificity
Water content: < 8% by Karl Fischer; Sodium content: 10.0 ± 2.0% by flame photometyl
Storage
Keep tightly stoppered in the dark below 5°C. Moisture will reduce the purity. For prolonged storage, keep below-20°C. Unstable in acids, but relatively stable at pH 10-11.
Synonyms
β-Nicotinamide-Adenine Dinucleotide Phosphate, Reduced; 2646-71-16; β-NADPH
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