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(-)-Epigallocatechin gallate
Cat No.
CEI-0676
Description
A polyphenol flavonoid that displays antitumor and antioxidant properties. Inhibits telomerase and DNA methyltransferase (DNMT) and blocks the activation of EGF receptors and HER-2 receptors. Also potently and specifically inhibits chymotrypsin-like activity of the proteasome in vitro (IC50= 86-194 nM) and in vivo (IC50 =1 -10 µM).
Alias
EGCG
Appearance
White solid
Product Overview
An antioxidant
CAS No.
989-51-5
Molecular Weight
548.63
Purity
>98% by HPLC
Storage
-20 centigrade
Synonyms
EGCG
Targets
DNMT1
Molecular Formula
C₂₂H₁₈O₁₁
Chemical Name
(2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate)
Solubility
DMSO (~50 mg/ml) or EtOH (~25 mg/ml)
Shipping Conditions
Gel pack
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