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(–)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase
Cat No.
EXWM-0816
Description
This cytochrome P450 enzyme, characterized from the plant Sinopodophyllum hexandrum, produces the direct precursor to etoposide, a potent anticancer drug. It can also act on (–)-deoxypodophyllotoxin with lower efficiency.
Form
Liquid or lyophilized powder
Enzyme Commission Number
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
CYP82D61 (gene name)
Reaction
(–)-4'-demethyldeoxypodophyllotoxin + NADPH + H+ + O2 = (–)-4'-demethylepipodophyllotoxin + NADP+ + H2O
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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