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Tirzepatide
Cat No.
CEPP-010
Description
Tirzepatide is a glucose-dependent dual agonist of the glucagon-independent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor.GIP and GLP-1 are both natural enteric insulinotropic hormones that promote insulin secretion.Tirzepatide combines the effects of the 2 insulinotropic hormones into a single molecule, a 39 amino acid modified peptide.
Tirzepatide contains two unnatural amino acids (aminoisobutyric acid, Aib) at positions 2 and 13, a C-terminal amide, and a Lys residue at position 20, which is attached to 1,20-eicosanedioic acid via a linker.
Tirzepatide contains two unnatural amino acids (aminoisobutyric acid, Aib) at positions 2 and 13, a C-terminal amide, and a Lys residue at position 20, which is attached to 1,20-eicosanedioic acid via a linker.
Applications
Tirzepatide shares a similar sequence to semaglutide, with the lys side chain of the sequence bearing a PEG modification, which is a functional group of the peptide, as well as the ability to increase the water solubility of the sequence.The primary physiological function of Tirzepatide is that of a dual agonist of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor. It is being developed for the treatment of type 2 diabetes mellitus and has entered the clinical phase.
Appearance
White or off-white powder
Package
1G/Bottle, 10G/Bottle,50G/Bottle or at customers reqirement.
CAS No.
2023788-19-2
Storage
-20°C
Molecular Formula
C225H348N48O68
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