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Suramin Hexasodium Salt
Cat No.
CEI-0654
Description
A P2x and P2y purinergic receptor antagonist that displays antitumor, antiangiogenic and antiparasitic activities. Inhibits sirtuin 1, sirtuin 5 and topoisomerase II. Inhibits the cell surface binding of various growth factors including PDGF, EGF, FGFa and FGFb. Blocks association of G protein α and β/γ-subunits. Potent competitive inhibitor of reverse transcriptase and protects T lymphocytes against in vitro human immunodeficiency virus infection
Appearance
White solid
Product Overview
A P2x and P2y purinergic receptor antagonist
CAS No.
129-46-4
Molecular Weight
166.19
Purity
>98% by titration
Storage
+4 centigrade
Targets
SIRT1, SIRT5, TOP2A
Molecular Formula
C51H34N6Na6O23S6
Chemical Name
8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
Solubility
H₂O (100 mM)
Shipping Conditions
RT
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