Description
Cell-permeable. A selective, ATP-competitive inhibitor of Aurora B kinase in vitro (IC 50 values are 50 nM, 250 nM and 1 μM for Aurora B, C and A kinases respectively). Selective over a range of other kinases including cdk1 and PLK1 (IC 50 > 10 μM).
Appearance
White solid or clear, colorless film
Product Overview
A potent adenylyl cyclase inhibitor
Targets
Aurora B, C and A kinases
Molecular Formula
C 9 H 11 N 5 O
Chemical Name
9-(Tetrahydrofuran-2-yl)-9H-purin-6-amine
Shipping Conditions
Gel pack