Description
A small-molecule chemical inhibitor of Sonic hedgehog (Shh) signaling, that blocks hedgehog signaling through specific binding and blockade of Shh signaling factor. It is the first-characterized hedgehog inhibitor whose molecular mechanism of action is through blockade of Shh protein and not a subsequent factor of the hedgehog signaling cascades. Robotnikinin binds to the Shh-N terminal protein in a concentration-dependent fashion with a Kd of 9 µM.
Product Overview
A small-molecule chemical inhibitor of Sonic hedgehog (Shh) signaling
Molecular Formula
C₂₅H₂₇ClN₂O₄
Chemical Name
N-[(4-Chlorophenyl)methyl]-2-[(2R,6S,8E)-5, 12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl]acetamide
Shipping Conditions
Gel pack
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