Description
The enzyme is a membrane bound proton-translocating pyridine nucleotide transhydrogenase that couples the reversible reduction of NADP by NADH to an inward proton translocation across the membrane. In the bacterium Escherichia coli the enzyme provides a major source of cytosolic NADPH. Detoxification of reactive oxygen species in mitochondria by glutathione peroxidases depends on NADPH produced by this enzyme.
Form
Liquid or lyophilized powder
Enzyme Commission Number
EC 7.1.1.1 (Formerly EC 1.6.1.5)
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
pntA (gene name); pntB (gene name); NNT (gene name)
Reaction
NADPH + NAD+ + H+[side 1] = NADP+ + NADH + H+[side 2]
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.