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Nec-1s
Cat No.
CEI-0584
Description
A potent necroptosis inhibitor. Displays higher activity in inhibiting necroptosis in Jurkat cells than Nec-1 (EC₅₀ = 210 nM versus EC₅₀ = 490 nM), as well as showing no nonspecific cytotoxicity at high concentrations (~100 mM). More useful for in-cell and in vivo experiments compared to Nec-1.
Alias
7-Cl-O-Nec-1
Appearance
Liquid
Product Overview
A potent necroptosis inhibitor
Molecular Weight
277.7
Purity
>99% by HPLC
Storage
-20 centigrade
Synonyms
7-Cl-O-Nec-1
Targets
Necroptosis
Molecular Formula
C 13 H 12 ClN 3 O 2
Chemical Name
5-((7-Cl-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione)
Shipping Conditions
Gel pack
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