Description
Factor V activator for RVV contains fucose, mannose, galactose, glucosamine, and neuraminic acid. Factor V activating enzyme from RVV is an arginine esterase that is sensitive to diisopropyl fluorophosphate (DFP).
Abbr
Factor V activator, Native (Russell's viper venom)
Source
Russell's viper venom
Applications
Factor V activating enzyme from Russell’s viper venom (RVV) is a single-chain glycoprotein that is involved in the rapid clotting of blood. Factor V circulates in the blood as an inactive cofactor and must be activated by proteases such as Factor V activating enzyme from RVV 1. This product may be useful in studying the blood coagulation cascade as well as the inherited deficiency called parahemophilia
Form
lyophilized powder; Stabilized in albumin and sodium chloride.
Enzyme Commission Number
EC 3.4.21.95
Activity
20 units/mg protein
Unit Definition
One unit will increase the Factor V activity in 0.1 mL of fresh normal human plasma by at least 2× after incubation for 3 min at 37°C.
Synonyms
EC 3.4.21.95; Factor V Activating Enzyme; Snake venom factor V activator; 65522-14-7; Factor V activator
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