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Native Porcine NADase
Cat No.
NATE-0472
Description
In enzymology, a NAD+ nucleosidase (EC 3.2.2.5) is an enzyme that catalyzes the chemical reaction:NAD+ + H2O↔ ADP-ribose + nicotinamide. Thus, the two substrates of this enzyme are NAD+ and H2O, whereas its two products are ADP-ribose and nicotinamide. This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. This enzyme participates in nicotinate and nicotinamide metabolism and calcium signaling pathway.
Abbr
NADase, Native (Porcine)
Alias
NADase
Source
Porcine brain
Species
Porcine
Applications
NADase from porcine brain has been used in a study to investigate histidine and related compounds resulting from catalyzed ADP-riboslyation. It has also been used in a study to investigate the preparation of arylazide-substituted pyridine adenine dinucleotides for photoaffinity labeling.
Product Overview
NADase is a glycohydrolase that catalyzes ADP-ribose transfer.
Form
Acetone-dried powder
Enzyme Commission Number
EC 3.2.2.5
Activity
> 0.007 unit/mg solid
CAS No.
9032-65-9
Unit Definition
One unit will hydrolyze 1.0 μmole of β-NAD to nicotinamide and ADP-ribose per min at pH 7.3 at 37°C.
Storage
−20°C
Buffer
insoluble
Synonyms
NAD glycohydrolase; nicotinamide adenine dinucleotide glycohydrolase; β-NAD+ glycohydrolase; DPNase (ambiguous); NAD hydrolase (ambiguous); diphosphopyridine nucleosidase (ambiguous); nicotinamide adenine dinucleotide nucleosidase (ambiguous); NAD nucleosidase (ambiguous); DPN hydrolase (ambiguous); NADase (ambiguous); nga (gene name); EC 3.2.2.5; 9032-65-9
Download
Download Datasheet| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| EXWM-3987 | NAD+ glycohydrolase | EC 3.2.2.5 | 9025-46-1 | Inquiry |