Description
Formate dehydrogenase is involved in the stress response of plants and catalyzes the reduction of NAD+ to NADH.
Abbr
FDH, Native (Candida boidinii)
Alias
FDH; FDH I; FDH II; N-FDH
Applications
Formate Dehydrogenase (FDH) is used for diagnostics in large scale industrial pr ocesses. Its used in the production of an unnatural amino acid, tert-L-leucine, a component of some HIV protease and matrix metalloprotease inhibitors.
Product Overview
FDH is an abundant enzyme from yeast Candida boidinii (CbFDH) that plays an important role in the energy supply of methylotrophic microorganisms and in the stress response of plants.
Form
Type I, lyophilized powder; Type II, powder; Type III, clear brown liquid.
Enzyme Commission Number
EC 1.2.1.2
Activity
Type I, 5.0-15.0 units/mg protein; Type II, 0.3-0.6 units/mg; Type III, ~50 U/mL.
Unit Definition
One unit will oxidize 1.0 μmole of formate to CO2 per min in the presence of β-NAD at pH 7.6 at 37°C.
Synonyms
EC 1.2.1.2; 9028-85-7; formate-NAD oxidoreductase; FDH; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formate benzyl-viologen oxidoreductase; formic acid dehydrogenase
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