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Coenzyme Q10
Cat No.
COEC-013
Description
Coenzyme Q10 is an electron transport chain component of the mitochondria, which assists proton and electron transfer across the inner mitochondrial membrane. Studies indicate that Coenzyme Q10 can protect human endothelial cells from oxidative damage by modulating the nitric oxide pathway. In addition, Coenzyme Q10 inhibits LDL oxidation, a major process in the development of atherosclerosis. Coenzyme Q10 is known to suppress the down regulation of NOS3 (endothelial nitric oxide synthase, eNOS) and up-regulation of NOS2 (inducible nitric oxide synthase, iNOS). As a result of its ability to bind Ca2+, Coenzyme Q10 can transport this cation across artificial biomimetic membranes.
Applications
A mitochondrial transporter chain component
Appearance
Powder
Form
Solid
CAS No.
303-98-0
Molecular Weight
863.34
Purity
≥98%
Synonyms
CoQ10; Ubidecarenone; Ubiquinone-10; Q-10
Molecular Formula
C59H90O4
Melting Point
48-52° C
Solubility
Soluble in water (partly), ethanol (5 mM), chloroform (50 mg/ml), and DMF (~10 mg/ml).
Boiling Point
~869.0° C at 760 (Predicted)
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