Description
A potent histone deacetylase (HDAC) inhibitor (ID₅₀ values of 0.01 and 0.07 μM in vitro for HDAC1 and HDAC3, respectively). CBHA also induces apoptosis in nine different neuroblastoma cell lines in culture (0.5-4.0 μM) and completely suppresses neuroblastoma tumor growth in SCID mice at 200 mg/ kg.
Alias
m-Carboxycinnamic Acid bis-Hydroxamide
Product Overview
A potent HDAC1 and HDAC3 inhibitor
Synonyms
m-Carboxycinnamic Acid bis-Hydroxamide
Molecular Formula
C10H10N2O4
Chemical Name
N-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-benzamide
Shipping Conditions
Gel pack
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