Description
A synthetic peptide that irreversibly inhibits activity of caspase family proteases and blocks apoptosis. The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used in both in vitro and in vivo studies. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Alias
Z-VAD-FMK, Caspase-Family Inhibitor (fluoromethylketone)
Product Overview
Caspase family substrate
Synonyms
Z-VAD-FMK, Caspase-Family Inhibitor (fluoromethylketone)
Molecular Formula
C₂₂H₃₀N₃O₇F
Solubility
DMSO (25 mM) or Ethanol (26 mM)
Shipping Conditions
Gel pack
Amino Acid Sequence
Z-Val-Ala-Asp(OMe)-FMK