Products
Online Inquiry
Our Products Cannot Be Used As Medicines Directly For Personal Use.
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
Carboxypeptidase-B rat, Recombinant
Cat No.
NATE-0153
Description
Carboxypeptidase B (or peptidyl-L-lysine (-L-arginine) hydrolase) catalyzes the hydrolysis of the basic amino acids, lysine, arginine, and ornithine from the C-terminal position of polypeptides. It has been shown to be a single polypeptide of 34 kDa Da. Trypsin is capable of converting native enzyme to the active enzyme, carboxypeptidase B II in vitro. The optimum pH is found to be 9.0. The enzyme may be used for sequence analysis by successive cleavage of C-terminal basic amino acids. It can also be used as a serum marker for the diagnosis of acute pancreatitis.
Abbr
CPB1, Recombinant (Rat)
Alias
CPB1
Source
E. coli
Species
Rat
Applications
Carboxypeptidase B (EC 3.4.17.2, protaminase, pancreatic carboxypeptidase B, tissue carboxypeptidase B, peptidyl-L-lysine [L-arginine]hydrolase) is a carboxypeptidase that preferentially acts upon basic amino acids, such as arginine and lysine. This serum enzyme is also responsible for rapidly metabolizing the C5a protein into C5a des-Arg, with one less amino acid.
Product Overview
Caspase 3 is synthesized as a 32 kDa proenzyme. The active enzyme is a heterodimer of two large (17 kDa) subunits and two small (12 kDa) subunits.
Form
Lyophilized from 20 mM Tris, pH 8.0 + 50 mM NaCl.
Enzyme Commission Number
EC 3.4.17.2
Activity
50-55 units/mg protein carboxypeptidase B
CAS No.
9025-24-5
Storage
−20°C
Pathway
Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Protein digestion and absorption, organism-specific biosystem
Function
carboxypeptidase activity; metallocarboxypeptidase activity; zinc ion binding
Synonyms
carboxypeptidase B; protaminase; CPB1; pancreatic carboxypeptidase B; tissue carboxypeptidase B; peptidyl-L-lysine [L-arginine]hydrolase; EC 3.4.17.2; 9025-24-5
Download
Download Datasheet| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-0151 | Native Human Carboxypeptidase B | EC 3.4.17.2 | 9025-24-5 | Human pancreas | Inquiry |
| NATE-0152 | Native Porcine Carboxypeptidase B | EC 3.4.17.2 | 9025-24-5 | Porcine pancreas | Inquiry |
| NATE-0993 | Carboxypeptidase-B from rat, Recombinant | Pichia pastoris | Inquiry | ||
| NATE-1147 | Carboxypeptidase B from Porcine, Recombinant | EC 3.4.17.2 | Porcine | Inquiry |