Description
The integral membrane protein MadBfrom the anaerobic bacterium Malonomonas rubra is a component of the multienzyme complex EC 4.1.1.89, biotin-dependent malonate decarboxylase. The free energy of the decarboxylation reaction is used to pump Na+ out of the cell. The enzyme is a member of the Na+-translocating decarboxylase family, other members of which include EC 4.1.1.3 (oxaloacetate decarboxylase) and EC 4.1.1.41 (methylmalonyl-CoA decarboxylase).
Form
Liquid or lyophilized powder
Enzyme Commission Number
EC 7.2.4.1 (Formerly EC 4.3.99.2)
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
MadB; carboxybiotin protein decarboxylase
Reaction
a carboxybiotinyl-[protein] + n Na+in + H+out = CO2 + a biotinyl-[protein] + n Na+out (n = 1–2)
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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