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3-hydroxy acid dehydrogenase
Cat No.
EXWM-0300
Description
The enzyme, purified from the bacterium Escherichia coli and the yeast Saccharomyces cerevisiae, shows activity with a range of 3- and 4-carbon 3-hydroxy acids. The highest activity is seen with L-allo-threonine and D-threonine. The enzyme from Escherichia coli also shows high activity with L-serine, D-serine, (S)-3-hydroxy-2-methylpropanoate and (R)-3-hydroxy-2-methylpropanoate. The enzyme has no activity with NAD+ or L-threonine (cf. EC 1.1.1.103, L-threonine 3-dehydrogenase).
Form
Liquid or lyophilized powder
Enzyme Commission Number
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
ydfG (gene name); YMR226c (gene name)
Reaction
L-allo-threonine + NADP+ = aminoacetone + CO2 + NADPH + H+ (overall reaction); (1a) L-allo-threonine + NADP+ = L-2-amino-3-oxobutanoate + NADPH + H+; (1b) L-2-amino-3-oxobutanoate = aminoacetone + CO2 (spontaneous)
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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