Alias
Atacand, Blopress, Amias, Ratacand
Storage
2 years at -20centigrade Powder
Synonyms
Atacand, Blopress, Amias, Ratacand
Targets
angiotensin II receptor
Molecular Formula
C24H20N6O3
Solubility
DMSO 88 mg/mL, Water
In vitro
Candesartan binds with high specificity to the angiotensin II AT1 receptors in CHO-AT1 cells. Candesartan does not affect cell viability or proliferation but increases the expression of VEGF and interleukin-8 in the cultured medium of KU-19-19 cells. Candesartan (0.1 nM) could reduce the maximal contractile response to angiostensin II by approximately 50%.
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