S-adenosylmethionine synthetase, Recombinant

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Activity	Size	Price	Qty	Add to Cart	Sample	Inquiry
700 U/mg protein	10 mg	$525		Add to Cart		Inquiry

Cat No.

NATE-1151

Description

S-adenosylmethionine synthetase (EC 2.5.1.6) (also known as methionine adenosyltransferase (MAT)) is an enzyme that creates S-adenosylmethionine (AdoMet) by reacting methionine (a non-polar amino acid) and ATP (the basic currency of energy). AdoMet is a methyl donor for transmethylation. It gives away its methyl group and is also the propylamino donor in polyamine biosynthesis. S-adenosylmethionine synthetasecan be considered the rate-limiting step of the methionine cycle.

Abbr

MAT, Recombinant

Alias

Appearance

White powder, lyophilized

Product Overview

S-adenosylmethionine (SAM) is a methyl donor and allows DNA methylation. Once DNA is methylated, it switches the genes off and therefore, S-adenosylmethionine can be considered tocontrol gene expression. SAM is also involved in gene transcription, cell proliferation, and production ofsecondary metabolites. Hence SAM synthetase is fast becoming a drug target, inparticular for the following diseases: depression, dementia, vacuolar myelopathy, liver injury, migraine, osteoarthritis, and as a potential cancer chemopreventive agent.

Enzyme Commission Number

EC 2.5.1.6

CAS_No

9012-52-6

Molecular Weight

About 46kDa (SDS-PAGE detection)

Purity

>90% (SDS-PAGE test)

Isoelectric point

pH Stability

7.0-9.5

Storage

Redissolved in 30% glycerol, 4°C, store at -20°C/-80°C for long-term preservation, Avoid multiple freeze-thaw cycles.

Buffer

Tris buffer, pH8.0

Synonyms

EC 2.5.1.6; MAT; MATA1; SAMS; SAMS1; Methionine adenosyltransferase 1; S-adenosylmethioninesynthase isoform type-1; AdoMet synthase 1; MAT 1; Methionineadenosyltransferase I/III; MAT-I/III; MAT1A; AMS1

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
EXWM-2797	methionine adenosyltransferase	EC 2.5.1.6	9012-52-6		Inquiry

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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