Nanozymes-Based Ion Detection Services

In recent years, nanozymes have been developed for detecting ions due to their high sensitivity and selectivity to target metal ions. The catalytic activity (peroxidase or oxidase-like activity) of the nanozymes are significantly altered in the presence of target ions such as Cu²⁺, Ag⁺, Hg²⁺, CN⁻, F⁻ and others. A variety of nanozymes, including Ag, Ag / Cu, Au, sulfur-doped graphene quantum dots (GQDs), GQDs / Au, have been utilized to develop colorimetric and fluorometric sensors for the detection of ions. Compared with traditional ion detection methods, assays based on nanozyme are more portable, simple, and highly sensitive, they can detect metal ion concentrations as low as parts per trillion.

Creative Enzymes provides accurate detection of ions containing metal ions and nonmetallic ions based on nanozymes, to help our customers worldwide in the field of nanozymes. Our platform is equipped with cutting-edge facilities and professional experts to support research. Here, we provide various services according to customers' demands.

Metal Ion Detection with Nanozymes

• Many detection methods are highly sensitive and selective but time-consuming and require tedious sample preparation and sophisticated instruments. Thus, Creative Enzymes has developed a sensitive, selective and simple optical method for the detection of heavy metal ions in environmental samples. Using a variety of nanomaterials, metal ion colorimetric and fluorescence sensors for detecting nanomaterials have been developed.

Fig. 1 Ion detection with nanozymes.

• We develop nanozyme based probes for the detection of heavy metal ions, which are small in size, portable and require only simple equipment. Therefore, they can be used for on-site analysis in a wide range of climatic conditions.
• We also develop nanonetworks with a variety of simulated enzymatic properties, for the specific detection of Hg²⁺ and Pb²⁺ in water samples.
• We provide comprehensive and individual assays of inorganic and organic mercury species, using DNA-engineered metal with copper oxide nanocomposites to mimic oxidase activity.
• We also provide CuS hollow nanospheres with peroxidase mimic catalytic activity, they can be an efficient medium for enrichment and detection of Hg²⁺ through Hg-S bond formation.

Nonmetallic Ion Detection with Nanozymes

• Fluorine detection is important for environmental and biological applications. In recent years, the use of enzyme mimicking activity of nanomaterials to develop biosensors has become a research hotspot. Creative Enzymes developes a nanozyme platform, where the oxidase-like activity of CeO₂ nanozymes are significantly enhanced in the presence of fluoride.
• We develop a simple one-step synthesis of well-dispersed amorphous GO nanozymes, and apply them to the detection of CN^- ions.
• The concentration of thiocyanate (SCN⁻) in body fluids is a good indicator of potential and severe health problems, and we develop a visual SCN⁻ sensing method using gold quantum dots nanozymes.

Creative Enzymes provides cost-effect, high quality and hassle-free services to our clients worldwide. We provide our clients with direct access to our experts as well as prompt response to their inquiries. If you are interested in our services or have some questions, please feel free to contact us or make an online inquiry.