Kinase is the most critical and largest superfamily of drug targets, containing 518 members, and is a major research area in the pharmaceutical industry and academic research. Kinase signaling pathways are essential in regulating cell proliferation, metabolism, and death. Thus changes in kinase activity may lead to various disease morphologies, including cancer. Thus, the above-mentioned important features of kinases make them one of the target families in drug screening and discovery. Researchers have continuously increased kinases in the past few years as important drug recognition targets. To date, the FDA has approved a variety of kinase inhibitors. Kinases in living organisms are essential; they regulate many basic activities through phosphate groups, such as cell growth, division, and death.

Properly functioning kinases are central to the day-to-day functioning of cells. When they malfunction, they contribute to a host of serious diseases, including Alzheimer's disease, diabetes, cardiovascular disease, and many types of cancer. Therefore, the screening and analysis of kinases are of great significance.

To support the screening, discovery, and development of kinase drugs, Creative Enzymes provides you with a variety of kinase types and a series of kinase research solutions, from detection method development and screening to selective analysis. Kinase screening and analysis services can provide a variety of kinase types, from detection method development and high-throughput screening to selectivity analysis and a series of kinase research solutions. It can also provide customers with a variety of cell assay formats for various functional evaluations of drug-candidate compounds.

Figure 1 Hit Kinases Separated Into Kinase Families.^[1]

Creative Enzyme provides cell-based and Biochemical-based assays for kinase screening and analysis. We have rich experience in cell experiments and can provide enzyme activity assays, binding ability assays, interaction assays, IC50 determination, cell selectivity screening, compound screening assays, etc. Based on our extensive experience in enzyme research, we can provide assay development, high-throughput screening, and selectivity assays for your kinase-based drug discovery.

Our Advantages:

• Our assay targets over 600 kinases.
• We provide single-point and multi-concentration IC50 assays.
• Data can be delivered quickly.
• One-stop and customized service according to customer needs.
• Dedicated scientists for each project.

Creative Enzymes has rich experience in kinase enzyme research. With our professional scientists and the most advanced equipment, we can provide customers with the detection of various kinase screening and profiling with the fastest delivery time and the most accurate delivery results.

Please get in touch with us for specific project implementation content and time. If you want to know more service information, please feel free to contact us; Creative Enzymes will be your trusted partner.