What is Enzyme Screening from Natural Sources?

There are a large number of undiscovered and unstudied biological resources in nature, including many enzymes with unique enzymatic activities and specific properties. In recent years, researchers have begun to focus on screening enzymes from natural sources. It focuses mainly on the discovery and exploitation of plants, animals, microorganisms, and other biological resources. By screening these enzymes, more efficient, specific, and economically viable catalysts can be obtained. Secondly, compared to the modification of known enzymes, natural-source enzyme screening is more versatile and can uncover different types of enzymes from different organisms. In addition, natural-source enzyme screening methods do not rely on a priori knowledge and can provide innovative enzyme resources for new fields and applications. Although natural-source enzyme screening methods have made some research progress in the field of enzyme engineering, some challenges remain. First, effective screening and validation of enzymes with target activity and specificity is time- and resource-intensive. Secondly, the catalytic mechanism and structure of natural enzymes are usually complex and require in-depth research and understanding. In addition, the screened enzymes still require subsequent modification and optimization to improve their catalytic performance and stability.

Our Enzyme Screening from Natural Sources Services

Creative Enzymes provides screening services for enzymes of natural origin and is dedicated to the discovery of natural enzymes with specific properties and high catalytic activity. We offer many related services, including but not limited to the following service offerings:

Our Enzyme Screening from Natural Sources Services Process

We offer a one-stop service for screening enzymes from natural sources and may carry out the following service steps:

1. Sample collection: You provide samples from biodiverse environments such as soil, water, plants, animals, and microorganisms, or high selective pressure environments (for environments similar to the process conditions).
2. Enrichment culture and isolation: Take what they are good for and cast what they are resistant to, followed by dilution coating and line separation.
3. Enzyme activity screening: We will use a high-throughput screening method to identify catalytically active enzymes by measuring their activity in the samples. The primary screen will remove most of the non-target strains and try to retain promising candidates. The second screen uses accurate quantitative analytical methods to determine reaction rates, selectivity, and more. At the same time, we will be able to select different enzyme reaction systems and assays according to your needs.
4. Enzyme identification: By analyzing the screened samples, we will use different biochemical and molecular biology techniques to determine the enzyme species and properties. This will help to further understand the function and advantages of the enzyme.
5. Characterization: After determining the catalytic activity and properties of the enzyme, we will perform a comprehensive characterization including catalytic mechanism study, substrate specificity, and stability. This will help to assess the potential application value of the enzyme and the feasibility of industrial conversion.
6. Reporting and delivery: Finally, we will provide our clients with a detailed report including the results of enzyme screening, enzyme characterization, and analytical data. We will also provide purification of the enzyme as needed.

We provide natural source enzyme screening services. By exploring and exploiting the diversity of biological resources in nature, we can obtain more efficient and specific enzymes to provide better catalysts for biotechnology and industry. For more details about our natural source enzyme screening service, please contact us and let us customize the most suitable solution for you.