Diseases Imaging with Nanozymes

As a new type of artificial enzyme, the nanozyme not only has enzyme-like catalytic activity, but also exhibits unique photothermal properties, paramagnetic, fluorescence, and other physical properties of nanomaterials. By combining unique physicochemical properties with enzyme-like catalytic activity, nano-zymes have been extensively developed for disease imaging and detection, and they may have promising applications in precision medicine.

Applications of nanozymes in disease imaging and detection, including in vivo imaging, live cell and organelle imaging, and tissue imaging. Creative Enzymes offers products for the nanozyme and life science research markets, all designed with the hope of making a researcher's lab time simpler and more affordable.

Fig. 1 Nanozymes for diseases imaging.

Nanozymes for In Vivo Imaging

• In vivo imaging allows us to look deeply into the living subjects, bringing great opportunities for clinical diagnosis and research tools. We typically contrast materials to clearly show the functional structure of physiological structures based on the magnetic, optical, acoustic and / or nuclear properties of the nanozymes.
• Using the unique relaxation properties of nanozymes, Creative Enzymes not only achieves in vitro tumor tissue imaging, but also in vivo tumor magnetic resonance imaging (MRI).
• We also develop nanozyme probes, which have also been broadly developed for disease therapeutic monitoring.
• Besides cancer imaging diagnosis, we also use nanozymes to exploit for other diseases imaging, such as infections, inflammation and some neurological diseases.

Nanozymes for Live Cell and Organelle Imaging

• Cytology is an important method for the diagnosis of clinical diseases. Cells shed from blood, cerebrospinal fluid, spinal fluid, pleural fluid, and mucous fluid can provide a wealth of clinical information, including cell morphology, cell types, and cell ratios, that can be used for cancer screening.
• Creative Enzymes provides varieties of nanozymes, which may drive color reaction. So, it can be used for qualitative and quantitative analysis of cytological features.
• We also employ the catalytic activity of nanozymes to design real-time detection probes for organelle imaging in living cells.

Nanozymes for Tissue Imaging

• Peroxidase nanozymes catalyze the oxidation of colorimetry substrates such as 3,3,5,5-tetramethylbenzidine (TMB), diazo-aminobenzene (DAB), and o-phenylenediamine (OPD) to produce color reactions. Inspired by this, Creative Enzymes uses them to image identified biomarkers in tissue sections for the diagnosis of pathological diseases.
• In addition to enzyme-like activities, the unique physicochemical properties of nanozymes, such as luminescence, X-ray absorption, and paramagnetic properties, have also been widely used to image pathological tissues.

Based on a variety of strategies, Creative Enzymes is confident that it will be able to offer its name in disease imaging to customers around the world at competitive prices. There is no doubt that our services will facilitate the success of your project in a shorter period of time. If you are interested in our services or have some questions, please feel free to contact us or make an online inquiry.