Description
Folic Acid is an important cofactor in the transfer of one-carbon moieties and plays big role in formation of S-adenosyl methionine and in the synthesis and repair of DNA and RNA. Folate depletion causes disruption of DNA integrity and repair enhancing carcinogenesis by altering expression of critical tumor suppressor genes. Folic Acid is a substrate of DHFR.
Applications
An important cofactor in the transfer of one-carbon moieties plays role in formation of S-adenosyl met
Synonyms
Pteroylglutamic acid
Molecular Formula
C19H19N7O6
Solubility
Soluble in water (1.6 mg/ml), 1 M NaOH (50 mg/ml), methanol (slightly), diluted acids, and alkaline solutions.
Boiling Point
846.45° C (Predicted)
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