BIBF1120 is a triple angiokinase inhibitor. It blocks signaling through vascular endothelial growth factor receptors (VEGFR; IC50 values of 13 to 34 nM), platelet-derived growth factor receptors (PDGFR; IC50 values of 59 to 65 nM), and fibroblast growth factor receptors (FGFR; IC50 values of 37 to 610 nM).
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